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Is CHOLINESTERASE a valid Scrabble word?

Yes, CHOLINESTERASE is a valid word in US Scrabble and UK Scrabble, worth 19 points.

Base score before bonus squares; blank tiles score zero.

What does CHOLINESTERASE mean?

  1. noun

    an enzyme that hydrolyses acetylcholine (into choline and acetic acid)

Definitions from WordNet 3.1, Princeton University.

Points

19

Scrabble

21

Words With Friends

14

Letters

C (3) + H (4) + O (1) + L (1) + I (1) + N (1) + E (1) + S (1) + T (1) + E (1) + R (1) + A (1) + S (1) + E (1) = 19 points in Scrabble.

Dictionary status

  • Scrabble (US & Canada)Valid
  • Scrabble (UK & worldwide)Valid
  • Words With FriendsListed

Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.

Hooks for CHOLINESTERASE

Single letters that turn CHOLINESTERASE into another valid word in US Scrabble. Hooks let you extend a word already on the board.

Front hooks0

None — nothing can be added to the front.

Back hooks1

Words you can make from CHOLINESTERASE

The 60 highest-scoring words using these letters.

Study CHOLINESTERASE and related words

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