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Is EPISTASIS a valid Scrabble word?

Yes, EPISTASIS is a valid word in US Scrabble and UK Scrabble, worth 11 points.

Base score before bonus squares; blank tiles score zero.

What does EPISTASIS mean?

  1. noun

    the suppression of a gene by the effect of an unrelated gene

Definitions from WordNet 3.1, Princeton University.

Points

11

Scrabble

12

Words With Friends

9

Letters

E (1) + P (3) + I (1) + S (1) + T (1) + A (1) + S (1) + I (1) + S (1) = 11 points in Scrabble.

Dictionary status

  • Scrabble (US & Canada)Valid
  • Scrabble (UK & worldwide)Valid
  • Words With FriendsListed

Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.

Hooks for EPISTASIS

EPISTASIS has no one-letter front or back hooks in US Scrabble. Adding a single letter to either end does not make another word in that list.

Front hooks0

None — nothing can be added to the front.

Back hooks0

None — nothing can be added to the end.

Words you can make from EPISTASIS

The 60 highest-scoring words using these letters.

Study EPISTASIS and related words

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