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Is ISOLEUCINE a valid Scrabble word?

Yes, ISOLEUCINE is a valid word in US Scrabble and UK Scrabble, worth 12 points.

Base score before bonus squares; blank tiles score zero.

What does ISOLEUCINE mean?

  1. noun

    an essential amino acid found in proteins; isomeric with leucine

Definitions from WordNet 3.1, Princeton University.

Points

12

Scrabble

16

Words With Friends

10

Letters

I (1) + S (1) + O (1) + L (1) + E (1) + U (1) + C (3) + I (1) + N (1) + E (1) = 12 points in Scrabble.

Dictionary status

  • Scrabble (US & Canada)Valid
  • Scrabble (UK & worldwide)Valid
  • Words With FriendsListed

Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.

Hooks for ISOLEUCINE

Single letters that turn ISOLEUCINE into another valid word in US Scrabble. Hooks let you extend a word already on the board.

Front hooks0

None — nothing can be added to the front.

Back hooks1

Words you can make from ISOLEUCINE

The 60 highest-scoring words using these letters.

Study ISOLEUCINE and related words

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