Is NUCLEASE a valid Scrabble word?
Yes, NUCLEASE is a valid word in US Scrabble and UK Scrabble, worth 10 points.
Base score before bonus squares; blank tiles score zero.
What does NUCLEASE mean?
- noun
general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units
Definitions from WordNet 3.1, Princeton University.
Points
- Scrabble
- 10
- Words With Friends
- 14
- Letters
- 8
N (1) + U (1) + C (3) + L (1) + E (1) + A (1) + S (1) + E (1) = 10 points in Scrabble.
Dictionary status
- Scrabble (US & Canada)Valid
- Scrabble (UK & worldwide)Valid
- Words With FriendsListed
Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.
Hooks for NUCLEASE
Single letters that turn NUCLEASE into another valid word in US Scrabble. Hooks let you extend a word already on the board.
Front hooks0
None. Nothing can be added to the front.
Back hooks1
Words you can make from NUCLEASE
The 60 highest-scoring words using these letters.
- censual9
- cleanse9
- enlaces9
- euclase9
- lacunes9
- launces9
- scalene9
- unlaces9
- caules8
- clause8
- cleans8
- cuneal8
- encase8
- enlace8
- lacune8
- lances8
- launce8
- seance8
- seneca8
- uncase8
- uncles8
- unlace8
- usance8
- acnes7
- alecs7
- canes7
- cauls7
- cause7
- cease7
- cense7
- clans7
- clean7
- clues7
- laces7
- lance7
- luces7
- sauce7
- scale7
- scena7
- scene7
- uncle7
- aeneus6
- aneles6
- unease6
- unseal6
- aces6
- acne6
- alec6
- cals6
- cane6
- cans6
- case6
- caul6
- cees6
- cels6
- clan6
- clue6
- cues6
- ecus6
- lace6
Study NUCLEASE and related words
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