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Is RIBONUCLEASE a valid Scrabble word?

Yes, RIBONUCLEASE is a valid word in US Scrabble and UK Scrabble, worth 16 points.

Base score before bonus squares; blank tiles score zero.

What does RIBONUCLEASE mean?

  1. noun

    a transferase that catalyzes the hydrolysis of ribonucleic acid

Definitions from WordNet 3.1, Princeton University.

Points

16

Scrabble

21

Words With Friends

12

Letters

R (1) + I (1) + B (3) + O (1) + N (1) + U (1) + C (3) + L (1) + E (1) + A (1) + S (1) + E (1) = 16 points in Scrabble.

Dictionary status

  • Scrabble (US & Canada)Valid
  • Scrabble (UK & worldwide)Valid
  • Words With FriendsListed

Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.

Hooks for RIBONUCLEASE

Single letters that turn RIBONUCLEASE into another valid word in US Scrabble. Hooks let you extend a word already on the board.

Front hooks0

None — nothing can be added to the front.

Back hooks1

Words you can make from RIBONUCLEASE

The 60 highest-scoring words using these letters.

Study RIBONUCLEASE and related words

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