Is ENDONUCLEASE a valid Scrabble word?
Yes, ENDONUCLEASE is a valid word in US Scrabble and UK Scrabble, worth 15 points.
Base score before bonus squares; blank tiles score zero.
What does ENDONUCLEASE mean?
- noun
a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes
Definitions from WordNet 3.1, Princeton University.
Points
15
Scrabble
20
Words With Friends
12
Letters
E (1) + N (1) + D (2) + O (1) + N (1) + U (1) + C (3) + L (1) + E (1) + A (1) + S (1) + E (1) = 15 points in Scrabble.
Dictionary status
- Scrabble (US & Canada)Valid
- Scrabble (UK & worldwide)Valid
- Words With FriendsListed
Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.
Hooks for ENDONUCLEASE
Single letters that turn ENDONUCLEASE into another valid word in US Scrabble. Hooks let you extend a word already on the board.
Front hooks0
None — nothing can be added to the front.
Back hooks1
Words you can make from ENDONUCLEASE
The 60 highest-scoring words using these letters.
- unenclosed13
- counseled12
- denounces12
- uncleaned12
- counselee11
- celadons11
- cleansed11
- coleseed11
- condense11
- denounce11
- enclosed11
- enounced11
- secondee11
- uncloned11
- unclosed11
- unscaled11
- alencons10
- enounces10
- lacunose10
- nuclease10
- nucleons10
- acnodes10
- calends10
- candles10
- caudles10
- cedulas10
- celadon10
- cleaned10
- coleads10
- deacons10
- decanes10
- decease10
- descale10
- eclosed10
- encased10
- encodes10
- enlaced10
- nuanced10
- scanned10
- seclude10
- seconde10
- solaced10
- uncased10
- unlaced10
- ensouled9
- unaneled9
- unleased9
- unsealed9
- alencon9
- ancones9
- cannels9
- censual9
- cleanse9
- coulees9
- counsel9
- enclose9
- enlaces9
- enounce9
- euclase9
- lacunes9
Study ENDONUCLEASE and related words
Have a full rack? Use the word finder to find every word you can play.