Is EXONUCLEASE a valid Scrabble word?
Yes, EXONUCLEASE is a valid word in US Scrabble and UK Scrabble, worth 20 points.
Base score before bonus squares; blank tiles score zero.
What does EXONUCLEASE mean?
- noun
a nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid
Definitions from WordNet 3.1, Princeton University.
Points
20
Scrabble
24
Words With Friends
11
Letters
E (1) + X (8) + O (1) + N (1) + U (1) + C (3) + L (1) + E (1) + A (1) + S (1) + E (1) = 20 points in Scrabble.
Dictionary status
- Scrabble (US & Canada)Valid
- Scrabble (UK & worldwide)Valid
- Words With FriendsListed
Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.
Hooks for EXONUCLEASE
Single letters that turn EXONUCLEASE into another valid word in US Scrabble. Hooks let you extend a word already on the board.
Front hooks0
None — nothing can be added to the front.
Back hooks1
Words you can make from EXONUCLEASE
The 60 highest-scoring words using these letters.
- claxons16
- culexes16
- calxes15
- claxon15
- coaxes15
- excels15
- excuse15
- scolex15
- coxae14
- coxal14
- coxes14
- culex14
- excel14
- execs14
- axones13
- sexual13
- calx13
- coax13
- coxa13
- exec13
- axels12
- axles12
- axone12
- axons12
- exons12
- laxes12
- lexes12
- loxes12
- luxes12
- nexus12
- unsex12
- cox12
- counselee11
- axel11
- axes11
- axle11
- axon11
- eaux11
- exes11
- exon11
- luxe11
- oxen11
- oxes11
- lacunose10
- nuclease10
- axe10
- lax10
- lex10
- lox10
- lux10
- sax10
- sex10
- sox10
- censual9
- cleanse9
- coulees9
- counsel9
- enclose9
- enlaces9
- euclase9
Study EXONUCLEASE and related words
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