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Is METHOTREXATES a valid Scrabble word?

Yes, METHOTREXATES is a valid word in US Scrabble and UK Scrabble, worth 25 points.

Base score before bonus squares; blank tiles score zero.

What does METHOTREXATES mean?

Methotrexates is a form of METHOTREXATE.

  1. noun

    toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis

Definitions from WordNet 3.1, Princeton University.

Points

Scrabble
25
Words With Friends
25
Letters
13

M (3) + E (1) + T (1) + H (4) + O (1) + T (1) + R (1) + E (1) + X (8) + A (1) + T (1) + E (1) + S (1) = 25 points in Scrabble.

Dictionary status

  • Scrabble (US & Canada)Valid
  • Scrabble (UK & worldwide)Valid
  • Words With FriendsListed

Scrabble lists: NWL2023 (US & Canada) and CSW24 (UK & worldwide). WWF uses our ENABLE reference plus verified additions. “Listed” and “Not listed” describe that reference; check acceptance in the game. Sources reviewed 2026-10-03.

Hooks for METHOTREXATES

METHOTREXATES has no one-letter front or back hooks in US Scrabble. Adding a single letter to either end does not make another word in that list.

Front hooks0

None. Nothing can be added to the front.

Back hooks0

None. Nothing can be added to the end.

Words you can make from METHOTREXATES

The 60 highest-scoring words using these letters.

Study METHOTREXATES and related words

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